Medetomidine may cause heart murmur in Cougars and Jaguars: case report

Authors

  • Thiago Cavalheri Luczinski Instituto Reprocon / R. João Vieira de Meneses, 1064, Campo Grande – MS, 79052-280, Brazil. https://orcid.org/0000-0002-4101-0470
  • Gediendson Ribeiro de Araújo Instituto Reprocon / R. João Vieira de Meneses, 1064, Campo Grande – MS, 79052-280, Brazil. https://orcid.org/0000-0002-6460-946X
  • Matheus Folgearini Silveira Federal Institute of Education, Science and Technology of Santa Catarina – Araquari Campus / Rodovia BR 280, km 27, Araquari - SC, 89245-000, Brazil. https://orcid.org/0000-0003-0091-0410
  • Murillo Daparé Kirnew School of Agricultural and Veterinarian Science, São Paulo State University / Via Prof Paulo Donato Castelane Castellane s/n, Jaboticabal - SP, 14884-900, Brazil. https://orcid.org/0000-0002-5217-3056
  • Roberto Andres Navarrete School of Agricultural and Veterinarian Science, São Paulo State University / Via Prof Paulo Donato Castelane Castellane s/n, Jaboticabal - SP, 14884-900, Brazil. https://orcid.org/0000-0002-9135-9769
  • Jorge Aparecido Salomão-Jr Faculty of Veterinary Medicine and Animal Science, University of São Paulo / Av. Prof. Dr. Orlando Marques de Paiva, 87, São Paulo – SP, 05508-270, Brazil.
  • Letícia Alecho Requena Instituto Reprocon / R. João Vieira de Meneses, 1064, Campo Grande – MS, 79052-280, Brazil. https://orcid.org/0000-0001-7695-567X
  • Jairo Antonio Melo dos Santos NEX – No Extinction Scientific Breeding Center / Fazenda Duas Pontes – BR 70, km 34, Corumbá de Goiás – GO, 72960-000, Brazil.
  • Marcell Hideki Koshiyama Faculty of Veterinary Medicine and Animal Science, University of São Paulo / Av. Prof. Dr. Orlando Marques de Paiva, 87, São Paulo – SP, 05508-270, Brazil. https://orcid.org/0000-0002-7464-7785
  • Cristiane Schilbach Pizzutto Faculty of Veterinary Medicine and Animal Science, University of São Paulo / Av. Prof. Dr. Orlando Marques de Paiva, 87, São Paulo – SP, 05508-270, Brazil. https://orcid.org/0000-0002-4357-5133
  • Pedro Nacib Jorge-Neto Instituto Reprocon / R. João Vieira de Meneses, 1064, Campo Grande – MS, 79052-280, Brazil. https://orcid.org/0000-0002-5894-0148

DOI:

https://doi.org/10.11609/jott.6098.12.14.17000-17002

Keywords:

α-2 adrenoceptor agonist, mitral valve regurgitation, trivial tricuspid valve regurgitation

Abstract

We report heart murmur in Jaguars and Cougars found during reproductive procedures for semen and oocyte collection.  Two male Cougars (n=2) and three female Jaguars (n=3) were examined.  Anesthesia was performed with ketamine and medetomidine in males.  Females also received propofol and were maintained with isoflurane.  The animals were evaluated during anesthetic monitoring with multiparameter monitor alongside clinical examination, ambulatory electrocardiogram and echocardiogram.  All animals presented mitral valve regurgitation under anesthesia, but without morphological changes in the cardiac structure or hemodynamic changes.  Medetomidine may cause transitory heart murmur in healthy Jaguars and Cougars. 

 

References

Araujo, G.R., T.A.R. Paula, T. Deco-Souza, R.M. Garay, L.C.F. Bergo, A.C. Csermak-Júnior, L.C. Silva & S.V.P. Alves (2015). Ocelot and oncilla spermatozoa can bind hen egg perivitelline membranes. Animal Reproduction Science 163: 56–62. https://doi.org/10.1016/j.anireprosci.2015.09.018

Araujo, G.R, T.A.R. Paula, T. Deco-Souza, R.G. Morato, L.C.F. Bergo, L.C. Silva, D.S. Costa & C. Braud (2018). Comparison of semen samples collected from wild and captive jaguars (Panthera onca) by urethral catheterization after pharmacological induction. Animal Reproduction Science 195(July 2017): 1–7. https://doi.org/10.1016/j.anireprosci.2017.12.019

Araujo, G.R., T.A.R. Paula, T. Deco-Souza, R.G. Morato, L.C.F. Bergo, L.C. Silva, P.N. Jorge-Neto & B.F.B. Sampaio (2020). Colheita farmacológica de sêmen de onças-pardas (Puma concolor: Mammalia: Carnivora: Felidae). Arquivo Brasileiro de Medicina Veterinária e Zootecnia 72(2): 437–442. https://doi.org/10.1590/1678-4162-11030

Carvalho, E.R., T. Champion, F. Ambrosini, G.A. Silva, G.C. Freitas & R.G.D.C. Vilani (2019). Dexmedetomidine low dose followed by constant rate infusion and antagonism by atipamezole in isoflurane-anesthetized cats: an echocardiographic study. Veterinary Anaesthesia and Analgesia 46(1): 43–54. https://doi.org/10.1016/j.vaa.2018.09.040

Cote, E., A.M. Manning, D. Emerson, N.J. Laste, R.L. Malakoff & N.K. Harpster (2004). Assessment of the prevalence of heart murmurs in overtly healthy cats. Journal of the American Veterinary Medical Association 225(3): 384–388. https://doi.org/10.2460/javma.2004.225.384

Jorge-Neto, P.N., T.C. Luczinski, G.R. Araújo, J.A. Salomão Júnior, A.S. Traldi, J.A.M. Santos, L.A. Requena, M.C.M. Gianni, T. Deco-Souza, C.S. Pizzutto & H. Baldassarre (2020). Can jaguar (Panthera onca) ovulate without copulation? Theriogenology 147: 57–61. https://doi.org/10.1016/j.theriogenology.2020.02.026

Miranda, G.M., M.L. Coelho, G.R. Araujo, M.C.C. Silva, P.N. Jorge Neto, A.C. Csermak Jr, J.A. Salomão Jr & T. Deco-Souza (2019). Sperm bank of free living jaguars: a tool for the ex situ conservation. In: Anais do XXVIII Encontro e XXII Congresso da Associação Brasileira de Veterinários de Animais Selvagens 1: 38–41

Rishniw, M. & W.P. Thomas (2002). Dynamic right ventricular outflow obstruction: A new cause of systolic murmurs in cats. Journal of Veterinary Internal Medicine 16(5): 547–552. https://doi.org/10.1111/j.1939-1676.2002.tb02385.x

Romagnoli, N., D. Zambelli, M. Cunto, C. Lambertini, D. Ventrella & M.B. Toaldo (2016). Non-invasive evaluation of the haemodynamic effects of high-dose medetomidine in healthy cats for semen collection. Journal of Feline Medicine and Surgery 18(4): 337–343. https://doi.org/10.1177/1098612X15583345

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Published

26-10-2020

Issue

Vol. 12 No. 14 (2020)

Section

Short Communications

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