Medetomidine may cause heart murmur in Cougars and Jaguars: case report

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Thiago Cavalheri Luczinski
Gediendson Ribeiro de Araújo
Matheus Folgearini Silveira
Murillo Daparé Kirnew
Roberto Andres Navarrete
Jorge Aparecido Salomão-Jr
Letícia Alecho Requena
Jairo Antonio Melo dos Santos
Marcell Hideki Koshiyama
Cristiane Schilbach Pizzutto
Pedro Nacib Jorge-Neto


We report heart murmur in Jaguars and Cougars found during reproductive procedures for semen and oocyte collection.  Two male Cougars (n=2) and three female Jaguars (n=3) were examined.  Anesthesia was performed with ketamine and medetomidine in males.  Females also received propofol and were maintained with isoflurane.  The animals were evaluated during anesthetic monitoring with multiparameter monitor alongside clinical examination, ambulatory electrocardiogram and echocardiogram.  All animals presented mitral valve regurgitation under anesthesia, but without morphological changes in the cardiac structure or hemodynamic changes.  Medetomidine may cause transitory heart murmur in healthy Jaguars and Cougars. 


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